Health science

 Following drug  combinations should not be prescribed simultaneously: 1. Phenobarbitone with warferin: It causes continuous bleeding  2.Erythromycin with warferin: It increases toxicity and Causing more bleeding.  3.Ciprofloxacin with olanzapine :plasma concentration  increase in our body  4.Nitroglcerine ,Isosobide nitrate  with  Tadafill,Silendenafil : causes very low B.P 5.Virapamil with Atenolol: decreased B.P and causing drug allergy 6.Lidocaine Hcl ( anaesthetic drug)                             with Beta blocker drugs   (metoprolol,Atenolol,Nebivolol,Bisoprolol,Acetubulol,Betaxolol,Esmolol): decreased heart rate causing low B.P 7.Tetracycline ( e.g Doxycycline) with Calcium gluconate injection : Toxicity increased causing Lever damage.  8.Potassium chloride with Spironolactone: Increases potassium level in blood causing dangerous effect.  9.Theophylli...

 There are three major causative factors are recognized: 1.Gram negative Helicobacter pylori 2.Increased Hcl secretion 3. Inadequate mucosa defence against gastric acid Treatment: 1. Antimicrobial agent: -Amoxicillin -Bismuth compound  -Clarithromycine -Metronidazole  -Tetracycline  2.H2 -receptor blockers -Cimetidine -Famotidine -Nizatidine -Ranitidine  3.proton pump inhibitors: -Esomeprazole -Lansoprazole -Omeprazole -Pantoprazole -Rabeprazole 4.Prostagladine: -misoprostol 5.Antimuscarinic agents: -Dicyclomine 6.Antacid: -Aluminum hydroxide -Calcium carbonate -Magnesium hydroxide -Sodium bicarbonate  7.Mucosal protective agent -Colloidal bismuth -Sucralfate Important  notes: -Cimentidine can potentiate the action of drugs like warferin,dizepam,phenytoin,quinine,carbamazipine,theophylline, imipramine therefore precautions  should take before administration of Cementide. 

Type of Hypertension, clinical manifestation and treatment: Blood pressure -BP is the force of blood pushing against the walls of blood vessels. Systolic blood pressure-Pressure in arteries when heart pump the blood. (120 mm Hg) Diastolic blood pressure-Pressure experienced in arteries when heart dialate.  Definition :Hypertension is condition in which the force of blood against arteries wall too high. Systolic blood pressure-Pressure greater than 140 mm Hg. Diastolic blood pressure: greater than 90 mmHg. Types of Hypertension: 1.Normal range: Systolic B.P less than 120mmHg                              Distolic B.P : less than 80 mmHg                            2.Prehypertension:120-139/80-89mmHg 3.Stage 1 Hypertension:140-159 /90-89mmHg 4.Stage 2 Hypertension:more than or equal to 160mmHg/ more than or equal to 100mmHg Cause of Hypertensi...

 Uses: 》Headaches            》Pain during menstrual period            》Toothache(Teeth pain)            》Bachaches ( Back pain)            》Osteoarthritis             》Cold/ flu aches and pain            》To reduce fever  Side effects:Rare  Precaution:          》If allergy to it          》If you have liver disease and Kidney disease           》Abuse of alcohol   INTERACTION;            It may interact with Ketoconazole  Overdose:symptoms of overdose: 》Nausea  vomiting, loss of appetite,sweating , 》Stomach/ abdominal pain  》Extreme tiredness 》Yellowish eyes/ Skin 》Dark Urine Note:Paracetamol ( acetaminophen) does not Cause stomach ulcer.But another pain kille...