SOME DRUG INTERACTION

 Following drug  combinations should not be prescribed simultaneously:

1. Phenobarbitone with warferin: It causes continuous bleeding 

2.Erythromycin with warferin: It increases toxicity and Causing more bleeding. 

3.Ciprofloxacin with olanzapine :plasma concentration  increase in our body 

4.Nitroglcerine ,Isosobide nitrate 
with
 Tadafill,Silendenafil : causes very low B.P

5.Virapamil with Atenolol: decreased B.P and causing drug allergy

6.Lidocaine Hcl ( anaesthetic drug)
                            with
Beta blocker drugs 
 (metoprolol,Atenolol,Nebivolol,Bisoprolol,Acetubulol,Betaxolol,Esmolol): decreased heart rate causing low B.P

7.Tetracycline ( e.g Doxycycline) with Calcium gluconate injection : Toxicity increased causing Lever damage. 

8.Potassium chloride with Spironolactone: Increases potassium level in blood causing dangerous effect. 

9.Theophylline with Ciprofloxacin : Increased toxicity causing Severe seizures. 

10.Pimozide with Ketoconazole : will Cause Severe allergy thereby seizures develop.

11.Aspirine with warferin: will Cause Severe bleeding. 

12.Proton pumpinhibitors( e.g Pantoprazole, Lansoprazole, Esomeprazole Rabeprazole  etc.) 
               With
H2 blockers ( Ranitidine, Cimetidine, Famotidine,Nizatidine): excessive decreased acid concentration causing Increased PH in stomach. 

13. Nasal Decongestant ( like Otrivine) 
with 
Amlodifine Atenolol: will increase blood pressure.

14.Warferine  with chlorophenicol: Toxicity will increase.

15. Tetracycline shouldn't take with milk.


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