Calculation of API in pharma manufacturing ll Formula!

 Calculation of Active pharmacetical ingredient:

Formula:

Batch size x Label claim x factor x 100 x 100

---------------------------------------------------------------------Assay % of API X (100-LOD)X 1000 X 1000

=....... (Z)

If quantity of 1st A. R no. is not sufficent then :

Avialable balance of 1st A. R no............ Kg(A)

Quantity required to be used from 2nd A. R No.

=Z-A=...... kg(B)

Calculation for 2nd A. R No.

=Bx1st Assay API x 1st(100-LOD%)

-------------------------------------------------=........Kg (C)

 Assay % of 2nd API x 2nd(100- LOD%)

Total quantity of API to be dispensed=

A+C=........... Kg.




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