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Calculation of API in pharma manufacturing ll Formula!

  Calculation of Active pharmacetical ingredient: Formula: Batch size x Label claim x factor x 100 x 100 ---------------------------------------------------------------------Assay % of API X (100-LOD)X 1000 X 1000 =....... (Z) If quantity of 1st A. R no. is not sufficent then : Avialable balance of 1st A. R no............ Kg(A) Quantity required to be used from 2nd A. R No. =Z-A=...... kg(B) Calculation for 2nd A. R No. =Bx1st Assay API x 1st(100-LOD%) -------------------------------------------------=........Kg (C)  Assay % of 2nd API x 2nd(100- LOD%) Total quantity of API to be dispensed= A+C=........... Kg.

Calculation of API (active pharmaceutical ingradient ) in pharma manufacturing

      Calculation of API of different AR no. 1.  A.R No.: rm0001 (let) Assay on anhydrous basis =A1 Water1 content : W1%(let) Required qty. Of API per Tablet =   Label claim x 100 x100x factor(if applicable )                     Assay1x (100-w1% )            = label claimx100x100x(f)                     A1x(100-w1%)                 = A1 mg. 2.  A.R No.: rm0002 (let)  A ssay on anhydrous basis =A2 mg Water1 content : W2%(let) Required qty. Of API per Tablet = Label claim x 100 x100xfactor(if applicable)             Assay2x (100-water2)            = label claimx100x100xf                     A1x(100-w1%)                 = A2 mg. 3.  A.R...

Cinnamon Water Medicinal Benefits: 7 Health Advantages of Drinking Dalchini Soaked Water Every Morning

 7  Medicinal Benefits of Drinking Cinnamon Water Every Morning:  If you are planning to add Cinnamon water to your daily morning routine, make sure to look at these 7 medicinal benefits of this drink:  o ne of the most desired benefits of cinnamon water is its potential to assist in weight loss. This spice boosts metabolism, enabling the body to burn calories more efficiently. Sipping on cinnamon-infused water can help control cravings, making it simpler to stick to a healthy eating plan. The polyphenols present in cinnamon might also aid in reducing body fat, particularly around the waist, making it a worthwhile addition to your weight management strategy. 1.Enhances Digestion: Cinnamon water is well-regarded for promoting better digestion. It contains compounds that stimulate the digestive system, encouraging the release of digestive enzymes. This can help relieve issues like bloating, gas, and indigestion. By enjoying cinnamon water in the morning, you set your ...

Garlic Medicinal Benefits: 5 Health Advantages of Eating 1 Raw Garlic Clove Daily On Empty Stomach

Garlic Medicinal Benefits: 5 Health Advantages of Eating 1 Raw Garlic Clove Daily On Empty Stomach : What happens in your body when you start eating 1 garlic clove daily in the morning? Check out these amazing 5 medicinal health benefits:     Boosts Immunity ?  One of the biggest perks of eating garlic daily is its power to strengthen your immune system. Garlic has compounds like allicin that can help enhance your body's ability to fight off infections. Regularly adding garlic to your diet can reduce the likelihood of catching colds or getting sick, making it especially useful during flu season. By making a garlic clove part of your morning routine, you're giving your body a little extra protection against common illnesses. R egulates Blood pressure  High blood pressure is a common issue that can have serious consequences. Thankfully, garlic has been found to positively influence blood pressure levels. Research shows that the sulfur compounds in garlic can help relax...

AAHYTHMIA DISEASE: Sign, Symptom &Treatment

An arrhythmia is an irregular heartbeat that may feel like a racing or fluttering heart. It is not always serious but can sometimes indicate a potentially fatal heart problem. Arrhythmias — sometimes called dysrhythmias — occur when the electrical signals that coordinate heartbeats are not working correctly. The heart may beat too quickly, too slowly, too early, or with an irregular rhythm. In contrast, a “normal sinus rhythm” refers to how the heart beats when it is working properly.

How potassium deficiency affects our heart

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Potassium is an essential nutrient for heart  health and should be made a part of a balanced diet. It not only helps reduce the risk of high blood pressure but also lowers the chances of developing Cardiovascular Diseases (CVDs) such as heart attack and stroke . As an electrolyte, potassium supports nerve and muscle function, regulates heart activity, and aids in the movement of nutrients and waste within your body's cells. While the connection between potassium and heart health is complex, it is well-established. Signs Of Potassium Deficiency: According to the Office of Dietary Supplements (ODS) of the National Institutes of Health (NIH), the daily requirement for potassium varies based on age and gender. For healthy adults aged 19-50, the recommended intake is 3,400 mg for males and 2,600 mg for females. For pregnant and lactating women, potassium requirements are a little higher, with 2,900 mg and 2,800 mg being the recommended amounts, respectively. If potassium levels in the b...

Sign,Symptom & Cause of heart attack!

Sign: Chest pain Heart attacks typically involve pain or discomfort in the chest’s middle or left side. It may feel like a tight, heavy squeezing, fullness, or uncomfortable pressure. Less commonly, it can feel like a sharp pain. Difficulty breathing Usually, this accompanies chest pain. However, shortness of breath may also begin before any chest discomfort. Upper body pain A person may feel pain or discomfort in one or both arms, typically the left one, which can radiate to the shoulders. This pain does not typically feel worse with movement, as with musculoskeletal or arthritis pain. There may also be pain in the neck, jaw, or back. Feeling lightheaded An individual may feel weak, faint, or break out into a cold sweat. Signs of a heart attack in females The following are common heart attack symptoms in females that can occur with or without chest pain: weakness that occurs suddenly extreme shortness of breath nausea, indigestion, or other digestive upsets all over body aches a gener...